Emergency Care for Patients on Amyloid-Targeting Therapies in Alzheimer's Disease

Authors

Thomas K. Hagerman, Henry Ford HealthFollow
Michelle Suh, University of ChicagoFollow
Gayatri Devi, Zucker School of MedicineFollow
Jennifer Sutherland, University of North Carolina HealthFollow
Gloria Chiang, Weill Cornell Medical CollegeFollow
Don Melady, Mount Sinai Hospital / GEDCFollow
Kevin Biese, University of North Carolina Medical School / GEDCFollow
Maura Kennedy, Harvard Medical SchoolFollow

Abstract

The introduction of novel amyloid-targeting therapies for Alzheimer’s disease presents challenges for emergency clinicians. Patients on these therapies may present with amyloid related imaging abnormalities (ARIA) that are only detectable on magnetic resonance imaging and have significant implications for emergency department (ED) pathways, particularly for patients with stroke-like symptoms and those requiring anticoagulants. In this article, we highlight key considerations for the practicing clinician and ED administrators, including the identification of ARIA, protocols for imaging and treatment considerations, and strategies for interdisciplinary collaboration to ensure optimal care for this unique patient population.

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This work is licensed under a Creative Commons Attribution-NonCommercial-No Derivative Works 4.0 International License.

Recommended Citation

Hagerman, Thomas K.; Suh, Michelle; Devi, Gayatri; Sutherland, Jennifer; Chiang, Gloria; Melady, Don; Biese, Kevin; and Kennedy, Maura (2024) "Emergency Care for Patients on Amyloid-Targeting Therapies in Alzheimer's Disease," Journal of Geriatric Emergency Medicine: Vol. 5: Iss. 3, Article 5.
DOI: https://doi.org/10.17294/2694-4715.1085
Available at: https://institutionalrepository.aah.org/jgem/vol5/iss3/5