Modeling post-operative survival in patients with gallbladder cancer resections: The road to improved patient care?

Affiliations

Lutheran General Hospital

Abstract

In this letter, we discuss the article by Li et al published in the World Journal of Gastrointestinal Surgery. Gallbladder cancer is a rare but fatal cancer that is often detected unexpectedly and at an advanced stage following routine cholecystectomy. Although the prognosis is poor, curative resections often combined with postoperative chemotherapy and/or radiation therapy can improve survival. However, targeted patient selection for the appropriate therapeutic approach is critical to minimize unnecessary morbidity. Using advanced statistical techniques, the authors developed a nomogram with the potential to predict survival after gallbladder cancer resection, identifying factors associated with long- and short-term survival. This tool could improve patient selection for surgery and post-operative treatment. In this letter, we provide background on survival nomograms including an in-depth discussion of statistical methods employed in this study, the use of nomograms in other forms of cancer, limitations to the model, and directions for future research.

Type

Letter

PubMed ID

40061964

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