Intraductal tubulopapillary neoplasm of the pancreas presenting as a localized pancreatic tumor in a 52-year-old woman: focusing on a rare pancreatic malignancy and contrasting to intrapapillary mucinous neoplasm


Internal Medicine, Advocate Lutheran General Hospital

Pathology, Advocate Lutheran General Hospital

Medical Oncology, Advocate Lutheran General Hospital


Intraductal tubulopapillary neoplasm (ITPN) is a distinctive type of pancreatic tumor first discovered more than three decades ago. ITPNs currently account for less than 1% of all pancreatic exocrine tumor cases recognized, and less than 5% of pancreatic intraductal tumors. A patient's presentation is often nonspecific in comparison to other intraductal pancreatic neoplasms. We discuss a 52-year-old female presenting with abdominal pain and weight loss with ITPN, and go on to define the typical presentation, clinical features, and pathology behind the tumor.

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