Pulmonary embolism (PE) in transit in heparin-induced thrombocytopenia (HIT) with negative serotonin-release assay (SRA)
Cheema T, Kieu T, Balek M, Ahmad M, Singh P. Pulmonary Embolism (PE) in Transit in Heparin-Induced Thrombocytopenia (HIT) With Negative Serotonin-Release Assay (SRA). Cureus. 2022;14(6):e25868. Published 2022 Jun 12. doi:10.7759/cureus.25868
Pulmonary embolism (PE) is a potentially lethal condition, although frequently diagnosed, and is rarely associated with transit on initial presentation. Heparin-induced thrombocytopenia (HIT) can cause both arterial thrombus formation and venous thromboembolism. The two forms of HIT must be differentiated in order to guide management. We present a complex and unique case of PE in transit secondary to HIT diagnosed in a patient with a negative serotonin assay.