Role of vasodilator therapy in acute heart failure

Authors

Aisha BatoolFollow
Negar Salehi
Shahzad Chaudhry, Advocate Aurora HealthFollow
Michael Cross
Abdallah Malkawi
Aisha Siraj

Recommended Citation

Batool A, Salehi N, Chaudhry S, Cross M, Malkawi A, Siraj A. Role of vasodilator therapy in acute heart failure. Cureus. 2021;13(8):e17126. doi: 10.7759/cureus.17126

Affiliations

Family Medicine, Aurora Health Center

Abstract

Over the past decade, several trials have questioned the efficacy of vasodilator therapy in acute heart failure (AHF) in the absence of uncontrolled hypertension. In this article, we provide a unique review of the most valuable four trials that present the role of vasodilator therapy in the management of patients with AHF. These four trials have evaluated the efficacy of different types of vasodilators such as nesiritide, ulatritide, and serelaxin in the setting of AHF. Also, we compared comprehensive vasodilator therapy versus standard therapy to see if there is any effect on mortality and re-hospitalization.

Document Type

Article

PubMed ID

34532168