Pulmonary hypertension and mitral regurgitation in an infant with an anatomically normal mitral valve
Hoang R, Cohen W, Mukadam S, et al. Pulmonary hypertension and mitral regurgitation in an infant with an anatomically normal mitral valve. Cardiol Young. 2021;31(3):476-478. doi:10.1017/S1047951120004059
A full-term, female presented on her date of birth with severe pulmonary hypertension (PH) and mitral regurgitation (MR), requiring veno-arterial extracorporeal membrane oxygenation. After the treatment, her PH and MR were resolved with no anatomic abnormality present. We propose a positive feedback loop of PH causing right ventricular dilation and interventricular septal shifts, worsening MR, and elevated left atrial, and potentially pulmonary, pressures.