The use of allograft bone morphogenetic protein in foot and ankle arthrodesis
DeVries JG, Scharer B. The use of allograft bone morphogenetic protein in foot and ankle arthrodesis. HSOA Journal of Orthopedic Research and Physiotherapy. 2016;2(1):023.
Bone grafting procedures continue to be an important and common surgery performed in the foot and ankle. Alternatives to autogenously harvested are continuously discovered and researched. A novel allogeneic morphogenetic protein harvesting process has shown promise in spine fusion surgery. A retrospective chart and radiographic review of the first 10 consecutive patients to utilize this graft was undertaken to determine initial outcomes and safety profile. Ultimately fusion was obtained in 90% (9 out of 10) of patients, and in 95.7% (22 out of 23) of arthrodesis sites. Weight bearing occurred at 59.9 ± 20.6 days, and radiographic union took place at 78.5 ± 42.4 days. Based on these initial results the graft appears safe and effective. Because of several inherent advantages of the graft, further study should be undertaken.