Platelet-rich plasma injection for rotator cuff disease
Loescher J, Guthmann R, Auten B. Platelet-rich plasma injection for rotator cuff disease. Can Fam Physician. 2020 Nov;66(11):824-826. PMID: 33208423
In non-operative treatment of rotator cuff injuries, PRP injection did not improve functional outcomes or pain scores when compared with saline solution placebo, dry needling, or corticosteroid injection (strength of recommendation A: systematic review of randomized controlled trials [RCTs] with some methodologic flaws). Surgical adjunctive PRP injection inconsistently produced statistically significant improvements in pain and function of minimal clinical significance (less than 5%) (strength of recommendation B: systematic review of RCTs). Overall, PRP injection in the treatment of rotator cuff disease showed inconsistent results with moderate to high risk of bias.