Association of dairy consumption with metabolic syndrome, hypertension and diabetes in 147 812 individuals from 21 countries

Authors

Balaji Bhavadharini, Hamilton Health Sciences
Mahshid Dehghan, Hamilton Health SciencesFollow
Andrew Mente, Hamilton Health Sciences
Sumathy Rangarajan, Hamilton Health Sciences
Patrick Sheridan, Hamilton Health Sciences
Viswanathan Mohan, Madras Diabetes Research Foundation
Romaina Iqbal, The Aga Khan University
Rajeev Gupta, Eternal Heart Care Centre and Research Institute
Scott Lear, Simon Fraser University
Edelweiss Wentzel-Viljoen, North-West University
Alvaro Avezum, Instituto Dante Pazzanese de CardiologiaFollow
Patricio Lopez-Jaramillo, Universidad de Santander
Prem Mony, St. John's Medical College
Ravi Prasad Varma, Achutha Menon Centre for Health Science Studies
Rajesh Kumar, Postgraduate Institute of Medical Education & Research, Chandigarh
Jephat Chifamba, University of ZimbabweFollow
Khalid F. Alhabib, King Saud UniversityFollow
Noushin Mohammadifard, Isfahan University of Medical Sciences
Aytekin Oguz, T.C. Saglik Bakanligi Istanbul Goztepe Egitim ve Arastirma Hastanesi
Fernando Lanas, Universidad de la Frontera
Dorota Rozanska, Wroclaw Medical University
Kristina Bengtsson Bostrom, Göteborgs Universitet
Khalid Yusoff, Universiti Teknologi MARA
Lungiswa P. Tsolkile, University of the Western Cape
Antonio Dans, University of the Philippines SystemFollow
Afzalhussein Yusufali, Dubai Health Authority
Andres Orlandini, Estudios Clinicos Latinoamerica
Paul Poirier, Institut universitaire de cardiologie et de pneumologie de Québec - Université Laval
Rasha Khatib, Advocate Aurora Health
Bo Hu, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College
Li Wei, Fuwai Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College
Lu Yin, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College

Abstract

Objective: Our aims were to assess the association of dairy intake with prevalence of metabolic syndrome (MetS) (cross-sectionally) and with incident hypertension and incident diabetes (prospectively) in a large multinational cohort study.

Methods: The Prospective Urban Rural Epidemiology (PURE) study is a prospective epidemiological study of individuals aged 35 and 70 years from 21 countries on five continents, with a median follow-up of 9.1 years. In the cross-sectional analyses, we assessed the association of dairy intake with prevalent MetS and its components among individuals with information on the five MetS components (n=112 922). For the prospective analyses, we examined the association of dairy with incident hypertension (in 57 547 individuals free of hypertension) and diabetes (in 131 481 individuals free of diabetes).

Results: In cross-sectional analysis, higher intake of total dairy (at least two servings/day compared with zero intake; OR 0.76, 95% CI 0.71 to 0.80, p-trend

Conclusions: Higher intake of whole fat (but not low fat) dairy was associated with a lower prevalence of MetS and most of its component factors, and with a lower incidence of hypertension and diabetes. Our findings should be evaluated in large randomized trials of the effects of whole fat dairy on the risks of MetS, hypertension, and diabetes.

Document Type

Article

PubMed ID

32423962

Link to Full Text

 

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