Fibrosing mediastinitis caused by histoplasmosis in an adolescent

Authors

Madhusudan Ganigara, Advocate Health - MidwestFollow
John J. Flores, University of Chicago
Jeremy Slivnick, Department of Medicine, The University of Chicago
Luis Landeras, University of Chicago
Narutoshi Hibino, Advocate Health - MidwestFollow
Barbara Hendrickson, University of Chicago
Aliya Husain, University of Chicago
Luca Vricella, Advocate Health - MidwestFollow
Michael G. Earing, Advocate Health - MidwestFollow

Recommended Citation

Ganigara M, Flores JJ, Slivnick J, et al. Fibrosing Mediastinitis Caused by Histoplasmosis in an Adolescent. JACC Case Rep. 2023;29(2):102161. Published 2023 Dec 13. doi:10.1016/j.jaccas.2023.102161

Abstract

Fibrosing mediastinitis (FM) is a rare, potentially progressive disease resulting from an idiosyncratic immune response to a variety of stimuli that lead to fibrous infiltration of the mediastinum and possible narrowing of the bronchovascular structures. We report an unusual case of FM in a pediatric patient presenting as myopericarditis and progressing to pericardial thickening and encasement of the mediastinal vascular structures needing surgical intervention. Imaging, including transthoracic echocardiography, cardiac computed tomography, and cardiac magnetic resonance played a crucial role in the diagnosis, assessment, and follow-up. Contrast-enhanced computed tomography can be especially helpful to demonstrate potential findings associated with FM.

Type

Article

PubMed ID

38264300