Clindamycin-induced dermatitis and the sparing phenomenon: A case report

Affiliations

Advocate Lutheran General Hosiptal

Abstract

Drug-induced dermatitis is a type IV, T-cell-mediated, hypersensitivity reaction characterized by the development of a rash in response to drug exposure. The sparing phenomenon, where drug-induced rash spares areas of recent skin disease, is a recognized but relatively rare clinical observation. In this report, a 62-year-old woman presented to the emergency department with drug-induced dermatitis secondary to clindamycin that spared a recent site of Pasteurella multocida cellulitis. This case visually highlights the complex interplay between T-cell activation and the local immune environment.

Type

Article

PubMed ID

41041099

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