Validation of R-hf risk score for risk stratification in ischemic heart failure patients: A prospective cohort study

Authors

Rajesh Rajan, Department of Cardiology, Sabah Al Ahmed Cardiac Centre, Kuwait City, Kuwait.
Suman Omana Soman, Department of Cardiology, Badr Al Samaa Hospital, Ruwi, Muscat, Oman.
Mohammed Al Jarallah, Department of Cardiology, Sabah Al Ahmed Cardiac Centre, Kuwait City, Kuwait.Follow
Zhanna Kobalava, Department of Internal Diseases with Courses of Cardiology and Functional Diagnostics, Peoples' Friendship University of Russia (RUDN University), Moscow, Russia.
Raja Dashti, Department of Cardiology, Sabah Al Ahmed Cardiac Centre, Kuwait City, Kuwait.Follow
Ibrahim Al Zakwani, Department of Pharmacology & Clinical Pharmacy, College of Medicine & Health Sciences, Sultan Qaboos University, Muscat, Oman.
Joud Al Balool, Faculty of Medicine, Kuwait University, Jabria, Kuwait.Follow
Gary Tse, Cardiovascular Analytics Group, Hong Kong, China, Tianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular Disease, Department of Cardiology, Tianjin Institute of Cardiology, Second Hospital of Tianjin Medical University, Tianjin, 300211, China.
Parul Setiya, Department of Agrometeorology, College of Agriculture, G.B.Pant University of Agriculture & Technology, Pantnagar, Uttarakhand, India.
Peter A. Brady, Advocate Aurora HealthFollow
Ahmad Al-Saber, Department of Mathematics and Statistics, University of Strathclyde, Glasgow, G1 1XH, UK.Follow
Govindan Vijayaraghavan, Department of Cardiology, Kerala Institute of Medical Sciences, Kerala, India.

Recommended Citation

Rajan R, Soman SO, Al Jarallah M, et al. Validation of R-hf risk score for risk stratification in ischemic heart failure patients: A prospective cohort study. Ann Med Surg (Lond). 2022;80:104333. Published 2022 Aug 5. doi:10.1016/j.amsu.2022.104333

Affiliations

Illinois Masonic Medical Center

Abstract

Background:The aim of this study was to validate R-heart failure (R-hf) risk score in ischemic heart failure patients.

Methods:We prospectively recruited a cohort of 179 ischemic and 107 non-ischemic heart failure patients. This study mainly focused on ischemic heart failure patients. Non-ischemic heart failure patients were included for the purpose of validation of the risk score in various heart failure groups. Patients were stratified in high risk, moderate risk and low risk groups according to R-hf risk score.

Results:A total of 179 participants with ischemic heart failure were included. Based on R-hf risk score, 82 had high risk, 50 had moderate risk and 47 had low risk heart failure scores. More than half of the patients having R-hf score of <5 had renal failure (n = 91, 50.8%) and anemia (n = 99, 55.3%). Notably, HFrEF was more prevalent in patients with high risk score (74, 90.2%). Patients with high risk score had significantly higher creatinine (2.63 ± 1.96, p < 0.001), Troponin-T HS (59.9 ± 38.0, p < 0.001) and PRO BNP (17842 ± 6684, p < 0.001) when compared to patients with low and moderate risk score. Patients with low risk score had significantly higher Hb (13.2 ± 1.85, p < 0.001), Albumin (3.69 ± 0.42, p < 0.001) and GFR (90.0 ± 8.04, p < 0.001). A R-hf score of <5 was a significant predictor of mortality in ischemic (OR = 50.34; 95% CI [16.94-194.00, p < 0.001) and non-ischemic (OR = 46.34; 95% CI [12.97-225.39], p < 0.001) heart failure patients.

Conclusions:Lower R-hf risk score is a significant predictor of mortality in ischemic and non-ischemic heart failure patients. Risk score can be accessed at https://www.hfriskcalc.in.

Type

Article

PubMed ID

35992211