Lung tumors marked percutaneously with indocyanine green dye-soaked embolization coils: A visual beacon for accurate intraoperative localization during lung sparing surgery

Authors

Edward J. Walsh, Grand Traverse Radiologists, Department of Radiology, Munson Medical Center, Traverse City, Michigan. Electronic address: ewalsh.md@gmail.com.
Hasnain Bawaadam, Advocate Health - MidwestFollow
Joseph G. Mammarappallil, Department of Radiology, Duke University Medical Center, Durham, North Carolina.
Jason R. Snider, Department of Radiology, Duke University Medical Center, Durham, North Carolina.
William C. Allsopp, Grand Traverse Radiologists, Department of Radiology, Munson Medical Center, Traverse City, Michigan.
Frederick J. Brodeur, Grand Traverse Radiologists, Department of Radiology, Munson Medical Center, Traverse City, Michigan.
Aaron R. Green, Grand Traverse Radiologists, Department of Radiology, Munson Medical Center, Traverse City, Michigan.
Ganesh Krishna, Division of Pulmonary, Critical Care, Allergy and Sleep Medicine, Department of Medicine, University of California, San Francisco, California; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Palo Alto Medical Foundation, Palo Alto, California.
Brandon M. Wojcik, Cardiothoracic Surgeons of Grand Traverse, Department of Surgery, Munson Medical Center, Traverse City, Michigan.

Recommended Citation

Walsh EJ, Bawaadam H, Mammarappallil JG, et al. Lung Tumors Marked Percutaneously with Indocyanine Green Dye-Soaked Embolization Coils: A Visual Beacon for Accurate Intraoperative Localization during Lung Sparing Surgery. J Vasc Interv Radiol. Published online September 4, 2025. doi:10.1016/j.jvir.2025.08.042

Affiliations

Advocate Aurora Medical Cener Kenosha

Abstract

Thoracic surgeons utilizing minimally invasive techniques for lung nodule resection often rely on localization markers to determine precise nodule location intraoperatively. Transbronchial or transthoracic injection of indocyanine green (ICG) dye has become a popular technique. However, surgery must be performed immediately as dye will dissipate to surrounding tissue. This multicenter retrospective study evaluated the efficacy of CT guided transthoracic placement of ICG dye-soaked coils (CT ICG-C) for preoperative lung nodule localization. Nineteen adult patients with 21 nodules underwent CT ICG-C placement from 03/01/2023 until 02/28/2025 at two medical centers. There were no adverse events. Median time from localization to surgery was 1 day (IQR 0-4 days), with 57.1% undergoing surgery >24 hours later. Localization success rate was 100%. CT ICG-C is a novel technique that allows for accurate nodule localization, delayed surgical resection, and the preservation of healthy lung tissue.

Document Type

Article

PubMed ID

40914488