The association between social engagement and cognition in older adults: Examining sex and ethnoracial group as moderators

Authors

Jasmine S. Dixon, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United Statesand.
Rebecca E. Amariglio, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United Statesand.
Marjorie Howard, Department of Biostatistics and Data Science, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States.
Kira Cella, Department of Clinical Nutrition, Rush University Medical Center, Chicago, Illinois, United States.
Sarah Tomaszewski Farias, Department of Neurology, University of California Davis, Davis, California, United States.
Masun J. Jackson, Advocate Health - MidwestFollow
Kristin R. Krueger, Rush Institute for Healthy Aging, Internal Medicine, Rush University Medical Center, Chicago, Illinois, United States.
Bonnie C. Sachs, Department of Neurology, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States.
Heather Snyder, Medical & Scientific Relations Division, Alzheimer's Association, Chicago, Illinois, United States.
Christy C. Tangney, Department of Clinical Nutrition and Department of Family & Preventive Medicine, Rush University Medical Center, Chicago, Illinois, United States.
Mark A. Espeland, Department of Biostatistics and Data Science, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States.
Laura D. Baker, Section of Gerontology and Geriatric Medicine, Department of Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, North Carolina, United States.
Kathryn Papp, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United Statesand.

Recommended Citation

Dixon JS, Amariglio RE, Howard M, et al. The association between social engagement and cognition in older adults: examining sex and ethnoracial group as moderators. J Gerontol B Psychol Sci Soc Sci. 2025;80(12):gbaf195. doi:10.1093/geronb/gbaf195

Abstract

Objectives: Recent research suggests that social engagement may be protective against cognitive decline and dementia. The current study examined the association between social engagement and cognition in a large, ethnoracially diverse cognitively unimpaired cohort of older adults selected for study inclusion based on multi-dimensional risk for cognitive decline.

Methods: We analyzed baseline data from a subset of older adults (N = 1,951; Mage = 68.2) who self-identified as non-Latinx White (n = 1,454), non-Latinx Black (n = 351), and Latinx (n = 146) participating in the U.S. POINTER clinical trial. Social engagement was measured using a composite score of seven items from the U.S. POINTER Physical and Mental Activity Questionnaire, and global cognition was assessed by a multi-domain cognitive composite. Associations between social engagement and cognition across the entire sample were examined, and secondarily, interactions between social engagement with sex and ethnoracial group.

Results: In the total sample, greater social engagement was associated with better global cognition. For female but not male participants, greater social engagement was associated with better global cognition. In contrast, the ethnoracial group was not a significant moderator.

Discussion: Greater social engagement was associated with better global cognition, and these associations varied by sex, but not ethnoracial group. Findings suggest that social engagement, a modifiable lifestyle factor, may be associated with better cognition in a sample of cognitively unimpaired older adults who are at increased risk of cognitive decline. Future research should examine the mechanisms that may influence why some individuals (ie, women) versus others benefit from increased social engagement in late life.

Document Type

Article

PubMed ID

41099822