Colon cancer: Feeling the imbalance?

Authors

Devesh S. Ballal, Advocate Health - MidwestFollow
Avanish P. Saklani, Division of Colo-Rectal and Peritoneal Surface Oncology, Department of Surgical Oncology, Tata Memorial Hospital, Mumbai, India.

Recommended Citation

Ballal DS, Saklani AP. Colon cancer: feeling the imbalance?. Colorectal Dis. Published online March 13, 2024. doi:10.1111/codi.16945

Affiliations

Advocate Lutheran General Hospital

Abstract

While neoadjuvant chemotherapy has become the standard of care for rectal cancers in most centres, there is much interest in neoadjuvant chemotherapy in colon cancer after the recent publication of the FOxTROT trial. The management of colon cancers seems to be heading down the same path as rectal cancer, where the radicality of surgery is replaced by chemotherapy intensification. The role of demanding procedures such as complete mesocolic excision with central venous ligation in this new paradigm of upfront chemotherapy remains uncertain and uninvestigated.

Document Type

Article

PubMed ID

38480511