A joint saga: Human leukocyte antigen (HLA) B27 ankylosing spondylitis and sacroiliitis association with Henoch-Schönlein purpura
Recommended Citation
Nassif ND, Rosler D. A joint saga: Human Leukocyte Antigen (HLA) B27 Ankylosing Spondylitis and Sacroiliitis Association with Henoch-Schönlein Purpura. Cureus. 2023;15(5):e39041. Published 2023 May 15. doi:10.7759/cureus.39041
Abstract
Henoch-Schönlein purpura (HSP) or IgA vasculitis is a small-vessel vasculitis mediated by IgA deposition, often associated with upper respiratory tract infection and family history. However, there is a rare correlation to human leukocyte antigen (HLA) B27 arthropathy. We present a case of a young boy diagnosed with HSP suffering from arthritis, gait disturbance, and weakness throughout childhood, ultimately diagnosed with ankylosing spondylitis and sacroiliitis clinically, with confirmation through X-ray and supporting HLA B27 testing.
Type
Article
PubMed ID
37378216