SARS-CoV-2 infection inducing immune thrombocytopenic purpura: case series

Authors

Nancy Guirguis, Advocate Aurora HealthFollow
Tyler Rehman, Advocate Aurora HealthFollow
Yara Shams, Advocate Aurora HealthFollow
Melanie Gordon, Advocate Aurora HealthFollow
Essam Mekhaiel, Advocate Aurora HealthFollow
Shaina Rozell, Advocate Aurora Health
Mauna Pandya

Recommended Citation

Guirguis N, Rehman T, Shams Y, Gordon M, Mekhaiel E, Rozell S, Pandya M. SARS-CoV-2 Infection Inducing Immune Thrombocytopenic Purpura: Case Series. Ochsner J. 2021 Summer;21(2):187-189. doi: 10.31486/toj.20.0100. PMID: 34239380; PMCID: PMC8238109

Affiliations

Advocate Christ Medical Center Internal Medicine Residency

Advocate Christ Medical Center

Abstract

Background: Immune thrombocytopenic purpura (ITP) refers to immune-mediated destruction of platelets. Viral infections have been proposed as an etiology of ITP; antibodies developed in response to infection may cross-react with normal platelets and result in their destruction.

Case Series: We report 2 cases in which coronavirus disease 2019 (COVID-19) likely induced severe ITP.

Conclusion: ITP may also play a role in the thrombocytopenia observed in some patients with COVID-19. ITP in this patient population may be more prevalent than currently documented.

Document Type

Article

PubMed ID

34239380