SARS-CoV-2 infection inducing immune thrombocytopenic purpura: case series
Guirguis N, Rehman T, Shams Y, Gordon M, Mekhaiel E, Rozell S, Pandya M. SARS-CoV-2 Infection Inducing Immune Thrombocytopenic Purpura: Case Series. Ochsner J. 2021 Summer;21(2):187-189. doi: 10.31486/toj.20.0100. PMID: 34239380; PMCID: PMC8238109
Background: Immune thrombocytopenic purpura (ITP) refers to immune-mediated destruction of platelets. Viral infections have been proposed as an etiology of ITP; antibodies developed in response to infection may cross-react with normal platelets and result in their destruction.
Case Series: We report 2 cases in which coronavirus disease 2019 (COVID-19) likely induced severe ITP.
Conclusion: ITP may also play a role in the thrombocytopenia observed in some patients with COVID-19. ITP in this patient population may be more prevalent than currently documented.