Understanding the Burden of Myocardial Infarction and Patient Preferences for Treatment: A Real-World Study Assessing Patients’ Perspectives via an Online Survey

Authors

M. Cecilia Bahit, INECO Neurociencias; Baim Institute for Clinical ResearchFollow
Serge Korjian, Harvard Medical SchoolFollow
Gerald Chi, Harvard Medical SchoolFollow
Yazan Daaboul, Baim Institute for Clinical ResearchFollow
Alberto Castro Molina, Baim Institute for Clinical ResearchFollow
Ginger Jiang, Baim Institute for Clinical Research; Harvard Medical SchoolFollow
Christiana Dangas, Baim Institute for Clinical ResearchFollow
Mudit Tandon, Carney Hospital, Dorchester, MAFollow
Deepak L. Bhatt, Icahn School of Medicine at Mount SinaiFollow
Roxana Mehran, Icahn School of Medicine at Mount SinaiFollow
Harriette G.C. van Spall, Baim Institute for Clinical Research; McMaster UniversityFollow
Paul Nara, CSL BehringFollow
Alka Shaunik, CSL BehringFollow
Charles Michael Gibson, Baim Institute for Clinical Research; Harvard Medical SchoolFollow

Publication Date

9-30-2025

Keywords

myocardial infarction, impact on patients, quality of life, quality improvement efforts

Abstract

Purpose: Myocardial infarction (MI) remains to be associated with a high risk of recurrent cardiovascular events and disease burden. This study assessed patient perspectives on the burden of disease and treatment in the first year post-MI.

Methods: Data were collected via a self-administered online questionnaire posted on the Carenity patient platform in the United States (10/30/2022−12/30/2022). Only patients who had an MI in the prior year were eligible for inclusion.

Results: A total of 151 patients completed the survey. The majority were men (69%), median age was 50 years, and 38% had an MI within the previous 90 days. Overall, post-MI complications were reported in 44% of the patients, including depression (23%), recurrent MI (7%), and stroke (7%). Follow-up care was provided by general/clinical cardiologists (67%), interventional cardiologists (38%), and general healthcare providers (59%). Most patients (80%) reported involvement in treatment decisions. The number of prescribed medications was considered the main contributor to post-MI treatment burden; approximately 42% of the patients found it tedious remembering to take their medications. The most commonly quoted post-MI treatment goal was recurrent MI risk reduction. Additionally, 73% of the patients considered improving quality of life to be a key goal. Overall, the patients’ emotional well-being, physical well-being, and personal life were particularly impacted by MI. “Stress/anxiety/fear” was the most frequently reported emotion immediately post-MI, and one-third conveyed MI’s negative impact on their employment status. MI impacted household finances in 74% of patients, with 38% losing income.

Conclusions: MI places a substantial burden on patients. Understanding patient experiences post-MI may enhance patient-centered care.

Recommended Citation

Cecilia Bahit M, Korjian S, Chi G, et al. Understanding the burden of myocardial infarction and patient preferences for treatment: a real-world study assessing patients’ perspectives via an online survey. J Patient Cent Res Rev. 2025;12:234-44. doi: 10.17294/2330-0698.2146