Predicting Outcomes in Patients With Atrial Fibrillation and Acute Mesenteric Ischemia

Authors

Sanjay Bhandari, Medical College of WisconsinFollow
Geetanjali Dang, Medical College of Wisconsin; Aurora Research InstituteFollow
Muhammad Shahreyar, Medical College of Wisconsin; Aurora Research InstituteFollow
Ahmad Hanif, Medical College of WisconsinFollow
Vijayadershan Muppidi, Medical College of WisconsinFollow
Atul Bhatia, Aurora Cardiovascular Services, Aurora Health Care; University of Wisconsin School of Medicine and Public HealthFollow
Jasbir Sra, Aurora Cardiovascular Services, Aurora Health Care; University of Wisconsin School of Medicine and Public HealthFollow
A. Jamil Tajik, Aurora Cardiovascular Services, Aurora Health Care; University of Wisconsin School of Medicine and Public HealthFollow
Arshad Jahangir, Sheikh Khalifa bin Hamad Al Thani Center for Integrative Research on Cardiovascular Aging, Aurora Research InstituteFollow

Publication Date

11-11-2016

Keywords

acute mesenteric ischemia, atrial fibrillation, anticoagulation, outcomes

Abstract

Purpose

Outcomes in patients with atrial fibrillation who develop acute mesenteric ischemia, and the impact of anticoagulation on complications, are not defined.

Methods

Patients admitted with acute mesenteric ischemia in the National Inpatient Sample from 2007, with and without atrial fibrillation, were compared for in-hospital outcomes using multivariate regression, and the impact of prior anticoagulation determined.

Results

Of 48,872 patients with acute mesenteric ischemia, 8,306 had atrial fibrillation, with 680 patients also on anticoagulation. Atrial fibrillation patients were more likely to be older and have hypertension, heart failure, or chronic lung or renal disease. After adjusting for potential confounders, atrial fibrillation remained independently associated with higher mortality (P < 0.001). Patients on anticoagulation were less likely to have intestinal resections or shock, less likely to need intubation and had lesser hospital stay and hospital charges compared to those not on anticoagulation.

Conclusions

In patients with acute mesenteric ischemia, presence of atrial fibrillation increases mortality, but prior anticoagulation reduces incidence of complications, length of stay and hospital charges.

Recommended Citation

Bhandari S, Dang G, Shahreyar M, Hanif A, Muppidi V, Bhatia A, Sra J, Tajik AJ, Jahangir A. Predicting outcomes in patients with atrial fibrillation and acute mesenteric ischemia. J Patient Cent Res Rev. 2016;3:177-86. doi: 10.17294/2330-0698.1285