intermittent fasting, calorie-restricted diet, lipids, diet, cholesterol, randomized controlled trials
With approximately 95 million Americans diagnosed with high cholesterol, and many searching for a nonmedicinal treatment, intermittent fasting as a method to improve health has become increasingly popular in the lay public. We conducted a clinical inquiry to determine whether intermittent fasting is superior to a low-calorie diet in improving lipids, searching the Cochrane, EBSCOhost, Embase, MEDLINE, and Scopus databases using the terms intermittent fasting, lipids, and calorie-restricted diet. Studies that included surgical weight loss or medicine-assisted weight loss were excluded. We identified 6 published studies, 5 of which were randomized controlled trials. In reviewing the selected studies, there did not appear to be a consistent difference in lipid change between restricted-calorie diet and intermittent fasting. Because of differences in study methods and in how intermittent fasting was defined, additional studies are needed.
Sanford MA, Sanford TS, Campbell KF, Davis D, Tandberg T, Eagle Road LN. Do adults utilizing intermittent fasting improve lipids more than those following a restricted-calorie diet? A Clin-IQ. J Patient Cent Res Rev. 2020;7:282-5. doi: 10.17294/2330-0698.1743
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December 23rd, 2019
April 20th, 2020